Sidi Lab - Publications

Ando K, Parsons MJ, Shah RB, Charendoff CI, Paris SL, Liu PH, Fassio SR, Rohrman BA, Thompson R, Oberst A, Sidi S*, Bouchier-Hayes L*.  NPM1 directs PIDDosome-dependent caspase-2 activation in the nucleolus.
J Cell Biol. 2017 Jun 5;216(6):1795-1810. doi: 10.1083/jcb.201608095. Epub 2017 Apr 21.
* equal contribution

Thompson R, Shah RN, Liu PH, Gupta YK, Ando K, Aggarwal AK, and Sidi S. An inhibitor of PIDDosome formation. Mol Cell 58, 767-779, 2015

Ando K, Kernan JL, Liu PH, Sanda T, Logette E, Tschopp J, Look AT, Wang J, Bouchier-Hayes L and Sidi S. PIDD death-domain phosphorylation by ATM controls prodeath versus prosurvival PIDDosome signaling. Mol Cell. 2012 Sep 14;47(5):681-93

Chen CC, Kennedy RD, Sidi S, Look AT and D’Andrea AD. Chk1 inhibition as a strategy for targeting fanconi anemia (FA) DNA repair pathway deficient tumors. Mol Cancer 8:24, doi:10.1186/1476-4598-8-24, 2009.

Sidi S, Sanda T, Kennedy RD, Hagen AT, Jette CA, Hoffmans R, Pascual J, Imamura S, Kishi S, Amatruda JF, Kanki JP, Green DR, D’Andrea AA and Look AT. Chk1 suppresses a caspase-2 apoptotic response to DNA damage that bypasses p53, Bcl-2 and caspase-3. Cell 133:864-877, 2008.

Obholzer N, Wolfson S, Trapani JG, Mo W, Nechiporuk A, Busch-Nentwich E, Seiler C, Sidi S, Sollner C, Duncan RN, Boehland A and Nicolson T. Vesicular glutamate transporter 3 is required for synaptic transmission in zebrafish hair cells. J. Neurosci 28: 2110-2118, 2008.

Julich D, Hwee Lim C, Round J, Nicolaije C, Schroeder J, Davies A, Geisler R, Lewis J, Jiang YJ, Holley SA; Tubingen 2000 Screen Consortium. beamter/deltaC and the role of Notch ligands in the zebrafish somite segmentation, hindbrain neurogenesis and hypochord differentiation. Dev Biol 286: 391-404, 2005.

Sidi S and Look, AT. Small molecules thwart crash and burn. Nat Chem Biol  1:351-353, 2005.

Shin JB, Adams D, Pauckert M, Siba M, Sidi S, Levin M, Gillespie P and Gruender S. Xenopus TRPN1 (NOMPC) localizes to microtubule-based cilia in epithelial cells, including inner-ear hair cells. Proc. Natl. Acad. Sci USA 102:12572-12577, 2005.

Julich D, Geisler R, Holley SA, Tubingen 2000 Screen Consortium. Integrinalpha5 and delta/notch signaling have complementary spatiotemporal requirements during zebrafish somitogenesis. Dev Cell 8:575-86, 2005.

Sidi S and Rosa FM. Mechanotransduction of hemodynamic forces regulates organogenesis. Med Sci (Paris) 20:557-561, 2004.

Sidi S, Busch-Nentwich E, Schönberger U, Friedrich RW and Nicolson T. gemini encodes a zebrafish L-type calcium channel that localizes at sensory hair cell ribbon synapses. J Neurosci 24:4213-4223, 2004.

Söllner C, Rauch GJ, Siemens J, Geisler R, Schuster C, The Tübingen 2000 Screen Consortium, Müller U and Nicolson T. Mutations in cadherin 23 affect tip links in zebrafish sensory hair cells. Nature 428:901-903, 2004.

Pauckert M, Sidi S, Russel C, Siba M, Wilson SW, Nicolson T and Gruender S. A family of acid-sensing ion channels (ASICs) from the zebrafish: widespread expression in the central nervous system suggests a conserved role in neuronal communication. J Biol Chem 279:18783-18791, 2004.

Seiler C Ben-David O Sidi S, Hendrich O, Rusch A, Burnside B, Avraham K and Nicolson T. Myosin VI is required for structural integrity of the apical surface of sensory hair cells in zebrafish. Dev Biol 272:328-338, 2004.

Sidi S, Friedrich RW and Nicolson T. NompC TRP channel required for vertebrate sensory hair cell mechanotransduction. Science 301:96-99, 2003.

Concha ML, Russel C, Regan JC, Tawk M, Sidi S, Gilmour DT, Kapsimali M, Sumoy L, Goldstone K, Amaya E, Kimelman D, Nicolson T, Gruender S, Gomperts M, Clarke JDW and Wilson SW. Local tissue interactions across the dorsal midline of the forebrain establish CNS laterality. Neuron 39:423-438, 2003.

Sidi S, Goutel C, Peyrieras N and Rosa FM. Maternal induction of ventral fate by zebrafish radar. Proc. Natl. Acad. Sci USA 100:3315-3320, 2003.

Willot V, Mathieu J, Lu Y, Schmid B, Sidi S, Yan YL, Postlethwait JH Mullins M, Rosa F and Peyrieras N. Cooperative action of ADMP- and BMP-mediated pathways in regulating cell fates in the zebrafish gastrula. Dev Biol 241:59-78, 2002.