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activities
http://icahn.mssm.edu/departments-and-institutes/developmental-and-regenerative-biology
 

Lemischka and Moore Labs - Activities

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principal investigator
invited presentations 2015/16
June 1-3, 2016
•	Ihor Lemischka, Li Fraumeni Society Meeting, invited speaker, Columbus, Ohio

August 25-28, 2016 
•	Kateri Moore, International Society for Experimental Hematology, 45th Annual Scientific Meeting, invited speaker, San Diego, CA

October 28-29, 2016
•	Kateri Moore, International Forum on Stem Cells, invited speaker, The St. Regis Tianjin, China
•	Ihor Lemischka, International Forum on Stem Cells, invited speaker, The St. Regis Tianjin, China

October 30, 2016
•	Kateri Moore, Beijing International Workshop on Hematopoietic Stem Cells, Institute of Zoology, Chinese Academy of Sciences, Beijing, China
•	Ihor Lemischka, Beijing International Workshop on Hematopoietic Stem Cells, Institute of Zoology, Chinese Academy of Sciences, Beijing, China

Faculty

January 29, 2016
•	Jeffrey Bernitz, NIH/NIDDK Workshop Effects of Aging on Hematopoiesis, poster presentation, Bethesda, MD

May 22-26, 2016
•	Jeffrey Bernitz, Norvo Nordisk, Stem Cell Niche – Development and Disease, poster presentation, Favrholm Campus, Hillerod, Denmark

August 25-28, 2016
•	Jeffrey Bernitz, International Society for Experimental Hematology, 45th Annual Scientific Meeting, oral and poster presentation, San Diego, CA
 -  Download Poster

•	Michael Daniel, International Society for Experimental Hematology, 45th Annual Scientific Meeting, poster presentation, San Diego, CA
 -  Download Posterhttp://drb.mssm.edu/lm/Aging%20Poster.pdfhttp://drb.mssm.edu/lm/ISEH%20Poster%202016.pdfshapeimage_20_link_0shapeimage_20_link_1

Graduate Students

press
Researchers Discover New Clues in the Development of Transplantable Stem Cells for Blood Disorders:
For scientists who study stem cells, the ability to produce hematopoietic stem/progenitor cells (HSPCs) in the lab and then transplant them into patients with blood disorders has been a long-sought-after goal. Recently, the field took a step closer to that milestone when researchers at the Icahn School of Medicine at Mount Sinai identified cells in the embryos and placentas of mice that are actually precursors to HSPCs. Hematopoiesis is the daily process by which the human body generates all of the different types of cells found in the blood and immunological system. 
The results of the team’s work—led by Kateri Moore, DVM, Associate Professor of Developmental and Regenerative Biology at the Icahn School of Medicine—were published online in the March 7, 2016, issue of Developmental Cell. The findings could eventually provide new information that will help develop patient-specific HSPCs and more differentiated blood products for cell-replacement therapy. 
In a previous study, Dr. Moore’s team successfully reprogrammed mouse skin cells to resemble HSPCs. That reprogramming process was used to inform the group’s latest research, which was focused on maturing precursor cells into hematopoietic stem/progenitor cells that are suitable for transplanting.

“INSIDE

Mount Sinai

Apr. 18 - May 1

2016

patents
Moore and Lemischka:  
Use of delta-like protein to inhibit the differentiation of stem cells.   Patent number: 6613565

Pereira, Moore, Lemischka:  
Pending:  Methods for Programming Differentiated Cells into Hematopoietic Stem Cells

Brosh and Lemischka:  
A dual molecular analog tuner for dissecting protein function in mammalian stem cells. Provisional Application No: 61/321,559
awards
•	Jeffrey Bernitz, F31 HL131290-01A1, Ruth L. Kirschstein Predoctoral Individual National Research Service Award, “Understanding How Proliferation Affects Hematopoietic Stem Cell Regenerative Potential”, 

•	Huen Suk Kim, F99 CA212489-01, The NCI Predoctoral to Postdoctoral Fellow Transition Award (F99/K00), “System analysis of p53 mutant associated cancer development with LFS patient-specific iPSCs”

•	Jeffrey Bernitz, selected as the Mount Sinai PhD in Biomedical Science nominee for the Harold M. Weintraub Graduate Student Award that recognizes outstanding graduate students in the Biomedical Sciences.

•	Michael Daniel, F31 HL136148-01, Ruth L. Kirschstein Predoctoral Individual National Research Service Award, “Zero Footprint Induction of Human Hemogenesis to Study Fanconi Anemia”.