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Zebrafish Shared Research Facility (Z-SRF)

facility info


Zebrafish Shared Research Facility


location:

Annenberg Building

1468 Madison Avenue

25th Floor, Room 220 & 29

New York, NY 10029


contacts:

Kirsten Sadler Edepli

ASSOCIATE PROFESSOR
kirsten.edepli@mssm.edu

tel: 212-241-7152

Evan Closser, Manager
evan.closser@mssm.edu

tel: 212-241-0227

 

Overview

    Zebrafish are a well-established vertebrate model for developmental studies and gene discovery and are emerging as a powerful system to model human disease. Their embryos are transparent and rapidly develop outside of the mother enabling detailed observation of developmental processes in real time using a dissecting microscope. The average clutch size is ~100 embryos, over 80% of which develop into mature animals in 5 days.  The high genetic conservation between zebrafish and humans and the similarities between mammalian and zebrafish organ development and function enables not only the elegant developmental studies but also studies of disease pathways and processes.  

 

    The Zebrafish Facility is directed by Dr. Kirsten Sadler Edepli and provides Mount Sinai researchers with an array of services:

  1. consultation with the facility director and manager to aid with experimental design and interpretation of results

  2. samples for pilot experiments, free of charge

  3. morpholino injection to deplete embryos of a gene of interest

  4. RNA injection for over expression in embryos

  5. importing mutant or transgenic lines upon request

  6. library of current mutant and transgenic stocks

  7. protocols for working with zebrafish embryos

  8. training investigators to carry out and analyze data using zebrafish

 

 
getting started


please contact:

Kirsten Sadler-Edepli
kirsten.edepli@mssm.edu

tel: 212-241-7152


and fill out form:

Zebrafish Core User Form

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announcements


See members of our lab at the following meetings:

August, 2012

November, 2012

January, 2013

June, 2013

October 6 - 8, 2013

October 16 - 18, 2013

December 11, 2013

May, 2014

June, 2014

FASEB Summer Research Conference

American Association for the Study of Liver Diseases

Zebrafish Investigators Meeting

36th Annual Research Society on Alcoholism Scientific Meeting, Orlando

Cancer Epigenomics Melia, Spain

1st Zebrafish for Personalized, Precision Medicine Conference Toronto, Canada

Mid-atlantic regional zebrafish meeting, Baltimore

Metabolism, Diet and Disease 2014: Cancer and metabolism Washington, DC

ZDM7, Madison WI