labslabs.htmlshapeimage_2_link_0
homehome.htmlshapeimage_3_link_0
facilitiesfacilities.htmlshapeimage_4_link_0
seminarsseminars.htmlshapeimage_5_link_0
linkslinks.htmlshapeimage_6_link_0
ezhkovaezhkova.htmlshapeimage_7_link_0
peopleezhkovalab.htmlshapeimage_8_link_0
publications
linksezhkovalink.htmlshapeimage_10_link_0
http://icahn.mssm.edu/departments-and-institutes/developmental-and-regenerative-biology
 

Ezhkova Lab - Publications

3ezhkova.html

Publications since:


2016

Polycomb-Mediated Repression and Sonic Hedgehog Signaling Interact to Regulate Merkel Cell Specification during Skin Development.

Perdigoto CN, Dauber KL, Bar C, Tsai PC, Valdes VJ, Cohen I, Santoriello FJ, Zhao D, Zheng D, Hsu YC, Ezhkova E.

PLoS Genet. 2016 Jul 14;12(7):e1006151. doi: 10.1371/journal.pgen.1006151. eCollection 2016 Jul.

PMID: 27414999


The mesenchymal transcription factor SNAI-1 instructs human liver specification.

Goldman O, Valdes VJ, Ezhkova E, Gouon-Evans V.

Stem Cell Res. 2016 May 21;17(1):62-68. doi: 10.1016/j.scr.2016.05.007. [Epub ahead of print]

PMID: 27240252 Free Article

Select item 26996938


Molecular Mechanisms Regulating Stem Cells Fate.

Chen YG, Ezhkova E, Ostankovitch M.

J Mol Biol. 2016 Apr 10;428(7):1407-8. doi: 10.1016/j.jmb.2016.03.011. Epub 2016 Mar 18. No abstract available.

PMID: 26996938

Select item 26994968


Dissecting the Roles of Polycomb Repressive Complex 2 Subunits in the Control of Skin Development.

Dauber KL, Perdigoto CN, Valdes VJ, Santoriello FJ, Cohen I, Ezhkova E.

J Invest Dermatol. 2016 Mar 16. pii: S0022-202X(16)30872-7. doi: 10.1016/j.jid.2016.02.809. [Epub ahead of print]

PMID: 26994968

Select item 26711501


Cbx4: A new guardian of p63's domain of epidermal control.

Cohen I, Ezhkova E.

J Cell Biol. 2016 Jan 4;212(1):9-11. doi: 10.1083/jcb.201512032. Epub 2015 Dec 28.

PMID: 26711501 Free PMC Article

Select item 25547114


2015

Terminal epidermal differentiation is regulated by the interaction of Fra-2/AP-1 with Ezh2 and ERK1/2.

Wurm S, Zhang J, Guinea-Viniegra J, García F, Muñoz J, Bakiri L, Ezhkova E, Wagner EF.

Genes Dev. 2015 Jan 15;29(2):144-56. doi: 10.1101/gad.249748.114. Epub 2014 Dec 29.

PMID: 25547114 Free PMC Article

Select item 25468937


2014

Embryonic maturation of epidermal Merkel cells is controlled by a redundant transcription factor network.

Perdigoto CN, Bardot ES, Valdes VJ, Santoriello FJ, Ezhkova E.

Development. 2014 Dec;141(24):4690-6. doi: 10.1242/dev.112169.

PMID: 25468937 Free PMC Article

Select item 25266660


The microRNA 424/503 cluster reduces CDC25A expression during cell cycle arrest imposed by transforming growth factor β in mammary epithelial cells.

Llobet-Navas D, Rodriguez-Barrueco R, de la Iglesia-Vicente J, Olivan M, Castro V, Saucedo-Cuevas L, Marshall N, Putcha P, Castillo-Martin M, Bardot E, Ezhkova E, Iavarone A, Cordon-Cardo C, Silva JM.

Mol Cell Biol. 2014 Dec 1;34(23):4216-31. doi: 10.1128/MCB.00611-14. Epub 2014 Sep 29.

PMID: 25266660 Free PMC Article

Select item 24636986


The miR-424(322)/503 cluster orchestrates remodeling of the epithelium in the involuting mammary gland.

Llobet-Navas D, Rodríguez-Barrueco R, Castro V, Ugalde AP, Sumazin P, Jacob-Sendler D, Demircan B, Castillo-Martín M, Putcha P, Marshall N, Villagrasa P, Chan J, Sanchez-Garcia F, Pe'er D, Rabadán R, Iavarone A, Cordón-Cardó C, Califano A, López-Otín C, Ezhkova E, Silva JM.

Genes Dev. 2014 Apr 1;28(7):765-82. doi: 10.1101/gad.237404.114. Epub 2014 Mar 17.

PMID: 24636986 Free PMC Article

Select item 24492849


Epigenetic regulation of epidermal differentiation.

Perdigoto CN, Valdes VJ, Bardot ES, Ezhkova E.

Cold Spring Harb Perspect Med. 2014 Feb 1;4(2). pii: a015263. doi: 10.1101/cshperspect.a015263. Review.

PMID: 24492849 Free PMC Article

Select item 23673358


2013

Polycomb subunits Ezh1 and Ezh2 regulate the Merkel cell differentiation program in skin stem cells.

Bardot ES, Valdes VJ, Zhang J, Perdigoto CN, Nicolis S, Hearn SA, Silva JM, Ezhkova E.

EMBO J. 2013 Jul 17;32(14):1990-2000. doi: 10.1038/emboj.2013.110. Epub 2013 May 14.

PMID: 23673358 Free PMC Article

Select item 23395438


SWItching on epidermal cell fate.

Perdigoto CN, Bardot ES, Ezhkova E.

Cell Stem Cell. 2013 Feb 7;12(2):141-2. doi: 10.1016/j.stem.2013.01.011.

PMID: 23395438 Free PMC Article

Select item 22314499


2012

Epigenetic regulation of skin: focus on the Polycomb complex.

Zhang J, Bardot E, Ezhkova E.

Cell Mol Life Sci. 2012 Jul;69(13):2161-72. doi: 10.1007/s00018-012-0920-x. Review.

PMID: 22314499 Free PMC Article

Select item 21680712


2011

Histone H2B ubiquitylation and H3 lysine 4 methylation prevent ectopic silencing of euchromatic loci important for the cellular response to heat.

Leung A, Cajigas I, Jia P, Ezhkova E, Brickner JH, Zhao Z, Geng F, Tansey WP.

Mol Biol Cell. 2011 Aug 1;22(15):2741-53. doi: 10.1091/mbc.E11-05-0426. Epub 2011 Jun 16.

PMID: 21680712 Free PMC Article

Select item 21317239


EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair.

Ezhkova E, Lien WH, Stokes N, Pasolli HA, Silva JM, Fuchs E.

Genes Dev. 2011 Mar 1;25(5):485-98. doi: 10.1101/gad.2019811. Epub 2011 Feb 11.

PMID: 21317239 Free PMC Article

Select item 20671696


2010

Regenerative medicine: An eye to treating blindness.

Ezhkova E, Fuchs E.

Nature. 2010 Jul 29;466(7306):567-8. doi: 10.1038/466567a. No abstract available.

PMID: 20671696 Free PMC Article

Select item 19524508


2009

Cyfip1 is a putative invasion suppressor in epithelial cancers.

Silva JM, Ezhkova E, Silva J, Heart S, Castillo M, Campos Y, Castro V, Bonilla F, Cordon-Cardo C, Muthuswamy SK, Powers S, Fuchs E, Hannon GJ.

Cell. 2009 Jun 12;137(6):1047-61. doi: 10.1016/j.cell.2009.04.013.

PMID: 19524508 Free PMC Article

Select item 19303854


Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells.

Ezhkova E, Pasolli HA, Parker JS, Stokes N, Su IH, Hannon G, Tarakhovsky A, Fuchs E.

Cell. 2009 Mar 20;136(6):1122-35. doi: 10.1016/j.cell.2008.12.043.

PMID: 19303854 Free PMC Article

Select item 16269334


2006

Chromatin immunoprecipitation to study protein-DNA interactions in budding yeast.

Ezhkova E, Tansey WP.

Methods Mol Biol. 2006;313:225-44.

PMID: 16118437

Select item 14967150


2005

The proteasome regulatory particle alters the SAGA coactivator to enhance its interactions with transcriptional activators.

Lee D, Ezhkova E, Li B, Pattenden SG, Tansey WP, Workman JL.

Cell. 2005 Nov 4;123(3):423-36.

PMID: 16269334 Free Article

Select item 16118437


2004

Proteasomal ATPases link ubiquitylation of histone H2B to methylation of histone H3.

Ezhkova E, Tansey WP.

Mol Cell. 2004 Feb 13;13(3):435-42.

PMID: 14967150 Free Article